Erythema multiforme
☆ Di encamên 2022-an de Stiftung Warentest ji Almanyayê, razîbûna xerîdar bi ModelDerm tenê ji şêwirmendên telemedicine drav hindik hindiktir bû.
Erythema multiforme minor - Bala xwe bidinê ku dibe ku navendên birînan şîn bibin.
Urticaria di heman demê de dibe ku wekî teşhîsek cûda were hesibandin.
References
Erythema multiforme (EM) rewşek e ku ji ber reaksiyonên xweparastinê deqên mîna armancê yên diyar hem li ser çerm û hem jî li ser membranên mûkozê xuya dibin. Her çend pir caran ji hêla enfeksiyonên vîrusî, nemaze virusê herpes simplex (HSV) , an hin dermanan ve têne rêve kirin, sedem di pir rewşan de nenas dimîne. Dermankirina EM-ya akût balê dikişîne ser sivikkirina nîşanan bi karanîna kremên ku steroîd an antihistamines hene. Birêvebirina EM-ê ya dûbare dema ku ji her nexweşek re hatî çêkirin herî bi bandor e. Nêzîkatiyên destpêkê hem dermankirinên devkî û hem jî yên topkî hene. Di nav wan de corticosteroids û dermanên antiviral hene. Dermankirinên herêmî ji kremên steroîdan ên bihêz û çareseriyên ji bo mûkozên bi bandor pêk tê. Ji bo nexweşên ku bersivê nadin antîvîrusan, vebijarkên rêza duyemîn dermanên çewisandina nesaxiyê, antîbiyotîk, anthelmintics, û antîmalariyan hene.
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Erythema multiforme (EM) is an immune-mediated condition that classically presents with discrete targetoid lesions and can involve both mucosal and cutaneous sites. While EM is typically preceded by viral infections, most notably herpes simplex virus (HSV), and certain medications, a large portion of cases are due to an unidentifiable cause. Treatment for acute EM is focused on relieving symptoms with topical steroids or antihistamines. Treatment for recurrent EM is most successful when tailored to individual patients. First line treatment for recurrent EM includes both systemic and topical therapies. Systemic therapies include corticosteroid therapy and antiviral prophylaxis. Topical therapies include high-potency corticosteroids, and antiseptic or anesthetic solutions for mucosal involvement. Second-line therapies for patients who do not respond to antiviral medications include immunosuppressive agents, antibiotics, anthelmintics, and antimalarials
Di gelek rewşan de, sivik erythema multiforme di nav 2 û 4 hefteyan de bi serê xwe diçe. Sendroma Stevens-Johnson, rewşek giran e ku bandorê li ser mûkozê dike, dikare heya 6 hefteyan bidome. Steroîd bi gelemperî ji bo rewşên sivik nayê pêşniyar kirin. Ma steroîd divê ji bo erythema multiforme ya giran were bikar anîn ne diyar e ji ber ku ji lêkolînên rasthatî vedîtinên zelal tune ku destnîşan dikin ka kîjan zarok dê ji vê dermankirinê sûd werbigirin.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
In most cases, mild erythema multiforme is self-limited and resolves in 2 to 4 weeks. Stevens-Johnson syndrome is a serious disease that involves the mucous membranes and lasts up to 6 weeks. There is no indication for using steroids for the mild form. Use of steroids for erythema multiforme major is debatable because no randomized studies clearly indicate which children will benefit from this treatment.
Em bûyerek erythema multiforme (EM) ya devkî ya ku ji hêla TMP/SMX ve hatî çêkirin pêşkêş dikin, ku birînên dev û lêvên tîpîk bêyî birînên çerm nîşan dide. Ev yek hewce dike ku ew ji nexweşiyên ulceratîf ên devkî yên din cuda bikin. Nexweş tedawiya nîşankirî û tabletên prednisolone wergirt, ku piştî rawestandina terapiya TMP / SMX dibe sedema başbûnê.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
We report a case of oral erythema multiforme (EM) secondary to TMP/SMX that presented with oral and lip ulcerations typical of EM without any skin lesions and highlights the importance of distinguishing them from other ulcerative disorders involving oral cavity. The patient was treated symptomatically and given tablet prednisolone. The condition improved with stoppage of TMP/SMX therapy.
Erythema multiforme reaksiyonek e ku çerm û carinan jî mûkoza têkildar dike, ku ji hêla pergala parastinê ve tê rêve kirin. Bi gelemperî, ew wekî birînên mîna mebestê xuya dike, ku dibe ku veqetandî xuya bikin, dubare bibin, an berdewam bikin. Van birîn bi gelemperî bi rengek sîmetrîk bandorê li lemlateyan dikin, nemaze rûkalên wan ên derve. Sedemên sereke enfeksiyonên mîna virusê herpes simplex û Mycoplasma pneumoniae, û her weha hin derman, vakslêdan, û nexweşiyên otoîmmune hene. Cûdahiya erythema multiforme ji urticaria bi dirêjahiya birînan ve girêdayî ye; Birînên erythema multiforme bi kêmî ve heft rojan sabît dimînin, dema ku birînên urticarial bi gelemperî di nav rojekê de winda dibin. Her çend dişibin hev, girîng e ku erythema multiforme ji sendroma dijwartir Stevens-Johnson, ku bi gelemperî makulên erythematoz an purpurîk ên berbelav bi bilbilan re peyda dike, cûda bikin. Birêvebirina erythema multiforme bi steroîdên topkî an antîhîstamînan re simptomatîkî û çareserkirina sedema bingehîn vedihewîne. Ji bo bûyerên dûbare yên ku bi vîrusa herpes simplex ve girêdayî ne, tedawiya antiviral a profîlaktîk tê pêşniyar kirin. Tevlêbûna giran a mukozê dibe ku pêdivî bi rakirina nexweşxaneyê ji bo şilavên intravenous û veguheztina elektrolîtê hebe.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Erythema multiforme is a reaction involving the skin and sometimes the mucosa, triggered by the immune system. Typically, it manifests as target-like lesions, which may appear isolated, recur, or persist. These lesions usually symmetrically affect the extremities, particularly their outer surfaces. The main causes include infections like herpes simplex virus and Mycoplasma pneumoniae, as well as certain medications, immunizations, and autoimmune diseases. Distinguishing erythema multiforme from urticaria relies on the duration of lesions; erythema multiforme lesions remain fixed for at least seven days, while urticarial lesions often vanish within a day. Although similar, it's crucial to differentiate erythema multiforme from the more severe Stevens-Johnson syndrome, which typically presents widespread erythematous or purpuric macules with blisters. Managing erythema multiforme involves symptomatic relief with topical steroids or antihistamines and addressing the underlying cause. For recurrent cases associated with herpes simplex virus, prophylactic antiviral therapy is recommended. Severe mucosal involvement may necessitate hospitalization for intravenous fluids and electrolyte replacement.
Ev rewş ji sivikek sivik, xwe-sînorkirî bigire heya formek giran, metirsîdar a jiyanê ku wekî erythema multiforme major tê zanîn ku di heman demê de perdeya mukozê jî digire, diguhere. Dagirkirina perdeya mukozê an jî hebûna bilbilan nîşanên girîng ên giraniyê ne.
- Erythema multiforme minor: Armancên tîpîk an bilindkirî, papulên edematoz bi akral têne belav kirin
Forma sivik bi gelemperî bi xurînek sivik (lê xiş dibe ku pir giran be), birînên pembe-sor, bi simetrîk hatine rêz kirin û li ser milan dest pê dikin, xuya dike. Di vê forma nexweşiyê de helkirina rashê di nav 7-10 rojan de norm e.
- Erythema multiforme major: Armancên tîpîk an bilindkirî, papulên edematoz bi tevlêbûna yek an çend membranên mukozê bi akral ve têne belav kirin. Veqetandina epidermal kêmtirî 10% ji tevahiya rûbera laş digire.
○ Dermankirin - Dermanên OTC
Ger bi tayê (zêdebûna germahiya laş) re hebe, tê pêşniyar kirin ku di zûtirîn dem de biçin nexweşxaneyê.
Divê dermanên gumanbar bêne sekinandin. (mînak antîbiyotîk, dermanên dijî-înflamatuar ên nesteroidal)
Antîhîstamînên devkî yên wekî cetirizine û loratadine ji bo xurandinê.
#Cetirizine [Zytec]
#LevoCetirizine [Xyzal]
#Loratadine [Claritin]